Author

Jie Hu

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Open access Sep 2026

Pharbitis nil Polysaccharide Ameliorate Ulcerative Colitis in Mice via Regulating Sphingolipid Metabolism

Objective This study aimed to investigate the therapeutic effects of Pharbitis nil polysaccharides (PNP) on ulcerative colitis (UC) and elucidate the underlying mechanisms. Methods PNP were extracted using water extraction and alcohol precipitation. Acute UC was induced in mice by administration of 3% dextran sulfate s...

Jie Hu, Dan Wu, Ming-Zhu Wu et al. · Natural Product Communicatio... · 0 citations

Review Open access Oct 2026

Unlocking the therapeutic potential of traditional Chinese medicine in Crohn’s disease: from multi-target mechanisms to clinical promise

Crohn’s disease (CD) is a chronic, relapsing inflammatory disorder of the gastrointestinal tract with an unclear etiology. Current Western therapies, including 5-aminosalicylates, corticosteroids, biologics, and immunomodulators, often fail to maintain sustained remission and are associated with significant adverse eff...

Meng'en Zhou, Yan Chen, Jie Hu et al. · Frontiers in Immunology · 0 citations