A Mitochondria-Targeted Iridium(III) Complex as a Potent Type-I/II Photosensitizer for Pyroptosis-Based Breast Cancer Therapy.
A "Swiss-army-knife" iridium(III) complex is reported that concurrently integrates mitochondria targeting, phosphorescence imaging, Type-I/II reactive oxygen species generation, photocatalytic oxidation of 1,4-dihydronicotinamide adenine dinucleotide (NADH) and pyroptosis induction, offering a "one-for-all" platform fo...