Reduced Exosomal miR-22 Promotes Cisplatin Resistance and Migration in Non-Small Cell Lung Cancer Cells Through MDM4 Upregulation
Background Cisplatin resistance remains a major obstacle in the treatment of non-small cell lung cancer (NSCLC). Exosome-mediated transfer of microRNAs contributes to tumor progression and chemotherapy resistance. However, the role of exosomal miR-22 in cisplatin resistance and its relationship with mouse double minute...