Open access
Oct 2026
Mitochondrial transfer protects against cisplatin-induced hearing loss by fumarate-mediated activation of mitophagy.
Sensorineural hearing loss (SNHL) affects millions of individuals worldwide, with platinum-based chemotherapeutics identified as a significant cause. In this study, we elucidate the mechanism by which mitochondrial transfer from mesenchymal stem/stromal cells (MSCs) protects against cisplatin-induced cochlear injury in...
Yun-Hao Wu, Yun-Hui Gu, Yu-Kai Wang et al.
· Cell Reports · 0 citations