Siglec Ligand Profiling on Extracellular Vesicles Reveals a Cancer-Related Signature with Immunosuppressive Function in Pancreatic Cancer.
Cancer-derived extracellular vesicles (EVs) act as systemic carriers of functional sialic acids and participate in local or distant immune escape via the Siglec pathway. Therefore, assessing the expression of Siglec ligands on EVs can facilitate the exploration of novel cancer biomarkers and enable the evaluation of ci...