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Preprint Sep 2026

Ultrafast light-sheet optical tweezers for in situ parallelized biomechanical characterization of cells and soft tissues

Quantitative characterization of the mechanical properties of cells and tissues is essential for understanding disease progression and tissue regeneration. Optical tweezers (OT) enable the direct application of biologically relevant forces; however, OT has been limited to single axial indentations of cells, thereby res...

Krishangi Krishna, Gannon Lemaster, Jie-Yi Xu et al. · 0 citations
Preprint Sep 2026

Structural identifiability and stress reconstruction from incomplete optical maps with velocimetry

Reconstructing the stress field of a planar viscoelastic flow from optical measurements loses its direct evidence wherever optical coverage is interrupted, and no improvement in optical precision restores an observation that was never made. We characterize what a second, velocity channel adds, and what neither channel...

Zi-Jian Liu, J. Olszewski, Bruce I. Gaynes et al. · 1 citation

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