Author

Jie Zhang

h-index 9 View on Semantic Scholar

We have 3 of 16 papers

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Review Open access Oct 2026

Senescence and tumor immunology: A multifaceted interplay of influence

Summary Medical advances and global population aging have propelled aging and cancer research into a new period of discovery. Senescent cells, which exert context-dependent tumor-suppressive and tumor-promoting effects, are central to this progress and engage in complex crosstalk with tumor proliferation. This review c...

Yuan Xie, Jie Zhang, Shi-Xiao Wang et al. · iScience · 0 citations

Open access Oct 2026

METTL14‐Mediated m6A Methylation Preserves Cardiomyocyte Homeostasis and Attenuates Progeria‐Associated Cardiac Remodeling

Hutchinson–Gilford progeria syndrome (HGPS) is a rare premature aging disorder most commonly caused by a de novo synonymous mutation (c.1824C>T) in the LMNA gene. This mutation activates aberrant splicing of prelamin A, leading to the production and accumulation of progerin, which drives accelerated aging, with patient...

Shi-Xiao Wang, Jie Zhang, Ying Ao et al. · Aging Cell · 0 citations

Open access Aug 2026

CK2α restriction of STING accumulation underlies systemic aging

This work identifies lamin A/C (LMNA) as a critical NE scaffold that orchestrates STING regulation by recruiting both STING and Casein Kinase 2 (CK2α), and establishes the LMNA-CK2-STING axis as a key biochemical mechanism that suppresses innate immune activation at the NE.

Jie Zhang, Mei-Ling Jin, Dan Rao et al. · Nature Communications · 0 citations