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Author

Jiekai Chen

2 papers indexed here

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Aug 2026

Integrin β6-Targeted CAR-T Cells exhibit potent antitumor activity in β6-Positive pancreatic ductal adenocarcinoma and lung adenocarcinoma.

Pancreatic ductal adenocarcinoma (PDAC) and lung adenocarcinoma (LUAD) remain lethal malignancies with limited therapeutic options, highlighting an urgent need for more effective treatments. Integrin αvβ6 (ITGB6) is a receptor preferentially expressed in specific types of tumors, such as PDAC and LUAD, and represents a...

Ling-Chao Shi, L. Qin, Shu-Xin Sun et al. · 0 citations
Open access Aug 2026

The landscape and plasticity of transposable element expression in an adult stem cell of high physiological and clinical significance

Transposable elements (TEs) contribute to diverse aspects of stem cell biology, particularly in germline and pluripotent stem cells, which typically exhibit more open chromatin. In human adult stem cells (ASCs), however, a comprehensive framework describing the landscape and plasticity of TE expression and how these...

Xingyu Fu, Qiangwei Cai, Jing-Jing Zhao et al. · 0 citations

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