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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Jiewei Wang

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Open access Aug 2026

OTUD5 maintains STAT1/2 stability and promotes IFNγ-driven intestinal inflammation

Using an intestinal epithelial cell -specific Otud5 KO mouse model, it is shown that Otud5 deficiency significantly alleviated the IFNγ-dependent colitis induced by dextran sulfate sodium, as evidenced by reduced weight loss and diminished infiltration of Ly6C+ inflammatory monocytes.

Huiyuan Guan, Changzhou Cai, Jiewei Wang et al. · 0 citations

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