Tris(2-ethylhexyl) trimellitate (TOTM) is a widely used plasticizer alternative to bis(2-ethylhexyl) phthalate in medical and consumer products, yet its toxicological profile remains poorly characterized. Given the increasing detection of TOTM in environmental matrices, concerns regarding its potential biological activ...
Yunchul Ihn, Yujin Park, Jihye Park et al.· Ecotoxicology and Environmen...· 0 citations
Promoter DNA hypermethylation is a key epigenetic mechanism of gene silencing in cancer, yet the DNA hypermethylome of oral squamous cell carcinoma (OSCC) and its prognostic relevance remain poorly characterized. Here, we systematically identified and validated novel hypermethylated genes with prognostic significance i...
Yu-Kyeong Han, Jihye Park, Hyemin Han et al.· Molecular Biomedicine· 0 citations
This work applied MLHeatmap to colorectal cancer consensus molecular subtype (CMS) classification using 511 primary tumors from The Cancer Genome Atlas with published Colorectal Cancer Subtyping Consortium (CRCSC) labels to support compact marker-panel discovery directly from count matrices.
Eun Young Lee, Jihye Park, S. Youn et al.· Bioinformatics Advances· 0 citations
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