Jillian Rundle

Saturated fatty acids enhance daptomycin activity in a Fak-dependent manner in enterococci

Abstract Antibiotic resistance of Gram-positive bacteria poses a major clinical challenge. Daptomycin, a lipopeptide antibiotic, is a treatment option for drug-resistant organisms. However, there have been clinical reports of daptomycin resistance and in vitro reports of daptomycin tolerance that can result in treatmen...