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Author

Jin-Chao Bi

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Oct 2026

STING hinders XIAP-mediated degradation of NLRP3 to lock the inflammasome in a hyperactivated state during pulmonary ischemia-reperfusion injury.

Pulmonary ischemia-reperfusion (I/R) injury activates the NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome to drive sterile inflammation. Although stimulator of interferon genes (STING) signaling primes NLRP3 transcription, its post-translational control over NLRP3 stability during lung I/R remai...

Tian Xia, Ming-Liang Wang, Dong Yang et al. · 0 citations

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