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Open access Sep 2026

Cartilage-targeting engineered probiotic bacterial extracellular vesicles treat osteoarthritis through modulation of matrix homeostasis

Reversing extracellular matrix (ECM) metabolic dysregulation to facilitate cartilage repair represents a key therapeutic strategy for osteoarthritis (OA) treatment. Owing to the avascular nature of joint structures, intra-articular injection is a commonly used clinical administration route. However, the current drug re...

Lu-Yu Niu, Wan-Zhuo Chen, Tong Liu et al. · 0 citations

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