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Author

Jin-Fang Ge

2 papers indexed here

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Open access Aug 2026

lncRNA TUG1 mediates palmitic acid-induced neuronal lipotoxic injury via the miR-449a-5p/caspase-3 and Akt/GSK-3β axes

A close relationship exists between excessive lipids and structural and functional brain dysfunction, with the long non-coding (lncRNA)-microRNA (miR)-mRNA network having an emerging role. Given the increasingly recognized role of the lncRNA taurine upregulated gene 1 (TUG1) in metabolic and neurodegenerative diseases,...

Yang-Wa Wei, Peng-Yao Chen, Xin Zheng et al. · 0 citations
Jul 2026

Role of Abca7-related microglial responses in linking type 2 diabetes mellitus to Alzheimer's Disease progression: Evidence from single-cell transcriptomic analysis and experimental validation in animal and cell models.

Results suggest Abca7 may play a linking role in the microglial response between T2DM and AD, which is partly supported by in vivo and in vitro results of its effect on the hyperactivation of microglia in AD-like pathologies.

Ming Cheng, Xin Zheng, Ya-Dong Wei et al. · 0 citations

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