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Author

Jinfen Zhang

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Open access Sep 2026

miR-125a-5p inhibits NF-κB by negatively regulating TRAF2 to alleviate inflammatory injury in ischemic stroke rats

The expression of certain miRNAs are significantly associated with both inflammatory and ischemia-reperfusion (I/R) injury in ischemic stroke. In this study, we identified cerebral cortex miR-125a-5p via RNA sequencing, which showed significant enrichment in inflammatory pathways. Cerebral infarction volume and neurolo...

Shou-Rui Niu, Chu-Jian Guo, Jin-Fen Zhang et al. · 0 citations
Open access Aug 2026

CircRNA_0004468 promotes VEGFA-mediated neurovascular repair by sponging miR-1224 in remote ischemic postconditioning against cerebral ischemia-reperfusion injury.

BACKGROUND Cerebral ischemia/reperfusion injury remains a major barrier to neurological recovery after recanalization therapy. Although remote ischemic postconditioning (RIPostC) has neuroprotective potential, its non-coding RNA mechanisms remain unclear. This study investigated whether the circular RNA 0004468 (circRN...

Chunyan Li, Chuang Liu, Yu-Xian Liu et al. · 0 citations

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