Review
Open access
Aug 2026
Imaging the fate of CAR-T cells in vivo
Despite the remarkable therapeutic efficacy of chimeric antigen receptor T (CAR-T) cell therapy in hematologic malignancies, its clinical translation in solid tumors remains impeded by challenges including insufficient intratumoral infiltration, tumor heterogeneity, and the immunosuppressive tumor microenvironment. Mol...
Hong-Yi Wang, Yan Yan, Yue-Ping Li et al.
· Frontiers in Immunology · 0 citations