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Author

Jin-He Guo

2 papers indexed here

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Open access Aug 2026

Machine Learning-Guided Personalized Immunochemotherapy Strategies in Intrahepatic Cholangiocarcinoma.

BACKGROUND & AIMS Immunochemotherapy (IO-chemo) has become standard care for patients with unresectable intrahepatic cholangiocarcinoma (iCCA), but benefit of adding IO varies greatly among individuals. We sought to develop a system to identify patients most likely to benefit from this treatment based on individualized...

Jun-Hao Mei, Kai Zhang, Ying Zhang et al. · 0 citations
Open access Sep 2026

IL-11 drives Treg cell differentiation by activating the MBD3/APOH-mediated fatty acid oxidation axis to promote hepatocellular carcinoma.

BACKGROUND The immunosuppressive tumor microenvironment (TME) represents a major barrier to effective hepatocellular carcinoma (HCC) therapy. While interleukin-11 (IL-11) has been implicated in cancer progression, its immunomodulatory functions and underlying mechanisms in HCC remain poorly understood. METHODS We eva...

Yang Gao, Xi-Juan Yao, Xing Huang et al. · 0 citations

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