Alveolar epithelial depletion of βPAK-interacting exchange factor drives spontaneous pulmonary fibrosis by impairing stemness
Aberrant repair/regeneration of alveolar epithelial stem cells is a key driver of pulmonary fibrosis (PF). While βPAK-interacting exchange factor (βPIX) is connected to stem cell signaling, its role in pulmonary fibrosis (PF) remains unknown. Here, we generated conditional βPIX knockout mice to investigate its contribu...