Author

Jin-Jun Bian

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Open access Sep 2026

Inflammation-mediated induction of Clec18a inhibits immune responses via Trpm7-dependent Cbl activation

Innate immune responses must be tightly controlled to maintain immuno-homeostasis. However, the regulatory mechanisms underlying the activation and early stages of the innate immune response remain poorly defined. Here, we found the soluble C-type lectin Clec18a is up-regulated in multiple inflammatory diseases, includ...

Zheng-Yu Jiang, Lu-Long Bo, Na Li et al. · bioRxiv · 0 citations

Open access Sep 2026

NMN Mitigates LPS-Induced Liver Injury by Inhibiting Ferroptosis via Suppression of the cGAS-STING-ACSL4 Axis.

Sepsis often leads to severe liver damage, and currently few effective therapies are available for it. Nicotinamide mononucleotide (NMN), a well-known anti-aging agent, exerts organ-protective effects, yet its detailed mechanisms against acute liver injury remain poorly understood. Here, we established LPS-induced live...

Yan Liao, Cheng-Long Zhu, Wangzheqi Zhang et al. · Pharmacological Research · 0 citations