ADP Inhibits Macrophage Senescence via the AMPK/KLF10 Pathway in Systemic Lupus Erythematosus
Lupus nephritis (LN) is a critical complication of systemic lupus erythematosus (SLE) and a leading cause of mortality in those affected. Abnormal energy metabolism of macrophages is closely associated with LN pathogenesis. Adenosine diphosphate (ADP) is known to regulate macrophage proinflammatory function; however, i...