Sep 2026
Discovery and mechanism analysis of novel TRPV1 antagonists driven by multi-dimensional virtual screening and dynamic simulation.
The transient receptor potential vanilloid type 1 (TRPV1) channel, a non-selective cation channel, is widely implicated in diverse physiological and pathological processes, including nociception and inflammation. Its modulators exert analgesic effects with a low risk of addiction, rendering TRPV1 a highly promising tar...
Yi-Xuan Guo, Zhi-Jiang Yang, Yi-Bo Liu et al.
· European journal of medicina... · 0 citations