Open access
Aug 2026
A multi-omics integrative analyses reveals CYBB-mediated apoptotic and immune dysregulation as a key target of berberine in diffuse large B-cell lymphoma
This integrative study identifies berberine-related genes with potential causal relevance to DLBCL and prioritizes CYBB as a functionally relevant target linked to apoptosis, immune regulation, and prognosis, highlighting the potential involvement of berberine–CYBB axis underlying berberine activity in DLBCL.
Jie-Wen Tan, Yun-Man Xu, Yue-Ping He et al.
· Frontiers in Pharmacology · 0 citations