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Jin-Ming Liu

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Sep 2026

An aptamer-regulated CRISPR/Cas12a system based on split crRNA for theophylline and tobramycin detection.

Most existing CRISPR/Cas12a methods for small molecules detection employ DNA aptamers as an intermediary, while RNA aptamers remain underexplored. The conventional CRISPR/Cas12 system offers limited programmability due to its partially conserved crRNA sequence. In this study, we developed an aptamer-regulated CRISPR/Ca...

Jin-Ming Liu, Le Li, Zi-Wen Tang et al. · 0 citations

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