Author

Jin-Ru Yang

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Review Open access Oct 2026

Metabolic immune checkpoints (MICs) in cancer: from molecular mechanisms to challenges and opportunities in clinical translation

Metabolic reprogramming is a core feature of tumor cells in adapting to microenvironmental stress and acquiring malignant phenotypes. It not only supports rapid proliferation but also mediates immune escape by reshaping the immune microenvironment. In recent years, the “metabolism-immune axis”, serving as a central hub...

Jin-Ru Yang, Xing Cai, Fa-Jian He et al. · Signal Transduction and Targ... · 0 citations

Open access Sep 2026

Interpretable Machine Learning Model for Fungal Infection Prediction: A Real‐World Study

A ML‐based model for FI prediction, demonstrating good predictive accuracy and strong clinical interpretability, is developed and validated and can assist clinicians in early identification of high‐risk patients and in making personalized intervention decisions, holding significant clinical value.

Jin-Ru Yang, Shu Pan, Tao Luo et al. · Health Care Science · 0 citations