Open access
Aug 2026
CEA-targeted CAR-NK cells derived from embryonic stem cells exhibit potent anti-tumor activity against colorectal cancer
Background Carcinoembryonic antigen (CEA) is overexpressed in most colorectal cancers (CRC) and serves as a promising immunotherapeutic target. However, current immune cell therapies against CRC show limited clinical efficacy, and the lack of renewable, standardized cell sources hampers broader application. The present...
Gao-Hua Li, Ling-Ping Zhao, Jing-Zhi Shen et al.
· Frontiers in Immunology · 0 citations