Neglected drivers of antibiotic resistance dissemination: promoted the horizontal transfer of antibiotic resistance genes by quorum sensing-mediated filamentous bacterial proliferation in activated sludge process.
Results indicated that filamentous bacterial quorum sensing was triggered by the increase in their population density, which significantly promoted production of extracellular proteins that could directly bind with antibiotics and ARGs, resulting in an increase in antibiotic stress and extracellular polymeric substance...