Iron metabolism and ferroptosis in ischemic stroke and intracerebral hemorrhage: a systematic review of mechanisms and modulation by natural products.
BACKGROUND Iron dyshomeostasis and phospholipid peroxidation contribute to secondary brain injury after ischemic stroke and intracerebral hemorrhage. Ferroptosis links these processes, but subtype-specific mechanisms and findings on natural-product interventions remain incompletely integrated. PURPOSE To systematical...