Author

Jin-Wei Zhang

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Oct 2026

Iterative dissolved-oxygen control combined with growth-production coordination enables efficient erythritol biosynthesis in Yarrowia lipolytica under high-temperature stress.

A comprehensive understanding of the growth-production trade-off under heat stress is essential for developing high-yield thermotolerant chassis. Here, the effects of elevated temperature on growth and erythritol biosynthesis were systematically investigated in YL (A high-erythritol-producing industrial Yarrowia lipoly...

Jin-Wei Zhang, Rui-Zeng Cao, Rui-Xi Xue et al. · Metabolic Engineering · 0 citations

Open access Oct 2026

RNA catalysis emerges from dynamic structural ensembles.

The dynamic interplay between RNA structure and its associated Mg2+ ions is central to RNA function yet remains poorly understood at a near-atomic level1-4. Here, using a heterogeneity-focused protocol for cryo-electron microscopy data analysis of conformationally flexible RNA particles, we determined the structures of...

M. Degenhardt, Hermann F. Degenhardt, Bapurao A. Bhoge et al. · Nature · 0 citations

Oct 2026

PNLDC1 deadenylase affects translational rate and cell proliferation in mESCs.

PNLDC1 is a member of the DEDD deadenylases, known for its specificity in poly(A) tail removal during mRNA turnover. While initially characterized for its function in pre-piRNA trimming critical to spermatogenesis and transposon silencing, its broader deadenylase activity which is especially pronounced during early dev...

Ilias Skeparnias, Athanasios-Nasir Shaukat, Christos Katsioulas et al. · RNA: A publication of the RN... · 0 citations