Temporal overlap of intraoperative hypotension and hypocapnia and postoperative outcomes after major open intracranial surgery: a time-weighted dual-hit cohort study
Background Intraoperative hypotension reduces cerebral perfusion pressure, whereas hypocapnia may reflect either ventilation-related cerebral vasoconstriction or reduced pulmonary perfusion during a low-flow state. We evaluated whether the time-weighted overlap of hypotension and hypocapnia was associated with adverse...