Development and Validation of a Sensitive UHPLC-MS/MS Analytical Method for Fulzerasib in Rat Plasma and its Application to Pharmacokinetics Studies.
The validated method was successfully applied in the first pharmacokinetic study of Fulzerasib in Sprague-Dawley rats following single intravenous and oral administration, and exhibited favorable pharmacokinetic properties, including low plasma clearance, moderate volume of distribution and notably high oral bioavailab...