Jinchen Jiang

Hijacked Pathways: PFOS, the ATF2/WT1 Axis, and the Mitochondrial Dysfunction in Sertoli Cells.

Perfluorooctane sulfonate (PFOS), a persistent organic pollutant, is associated with male reproductive disorders, yet its mechanisms remain poorly understood. Using in vivo (ICR mice exposed to 0.5, 5, and 10mg/kg/d PFOS for 28 days) and in vitro models, we investigated the role of the transcription factor 2 (ATF2) / W...