Author

Jin’e Li

2 papers indexed here

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Open access Aug 2026

Integrative analysis of gut microbiota, plasma metabolome, and gene expression identifies causal mediators in Graves’ disease pathogenesis

Background Graves’ disease (GD) is characterized by hyperthyroidism and is influenced by genetic and environmental factors. The “gut-thyroid axis” establishes a connection between the gut microbiota and GD, yet the underlying potential mechanisms remain unclear. This study employed Mendelian randomization to investigat...

Yuying Zhang, Jin’e Li, Yunfei Luo et al. · Frontiers in Microbiology · 0 citations

Jul 2026

METTL3‐Activated IDO1‐Kynurenine Pathway in Insulin‐Producing Cells Enhances Graft Survival and Attenuates Endogenous Islet Apoptosis in Diabetic Mice

It is shown that METTL3 overexpression is associated with IDO1 upregulation and elevated systemic Kyn levels, which suggest that the METTL3‐IDO1‐Kyn pathway may be a potential target for improving cell replacement therapy for diabetes.

Shan Xu, Li-Xuan Fang, Jia-Jun Qiu et al. · The FASEB Journal · 0 citations