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Review Open access Sep 2026

Central nervous system efficacy of third generation vs. first generation EGFR-TKIs in the first line treatment for EGFR-mutated non-small cell lung cancer with central nervous system metastases: a systematic review and meta-analysis of phase 3 randomized controlled trials

Background Epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC) with central nervous system (CNS) metastases poses significant treatment challenges, as first-generation EGFR-tyrosine kinase inhibitors (TKIs) (FGET) show limited CNS efficacy. Although third-generation EGFR-TKIs (TGET) exhibi...

Jiong-Li Gan, Shao-Feng Zhu, Yan Fang et al. · 0 citations
Case report Sep 2026

Ultrasound Diagnosis of Umbilical Artery Thrombosis in Late Pregnancy: A Case Report and Literature Review.

A case of UAT diagnosed by ultrasound and confirmed by cesarean section at the First Hospital of Nanchang is reported to remind sonographers to standardize image acquisition and improve awareness of UAT, thereby reducing the incidence of adverse pregnancy outcomes.

Ting Liu, Jing Cai · 0 citations

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