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Author

Jingchen Sun

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Oct 2026

BmSNX20 restricts Bombyx mori nucleopolyhedrovirus infection and is associated with autophagy-mediated antiviral immunity.

Sorting nexins (SNXs) are phosphoinositide-binding proteins that play critical roles in membrane trafficking and have been implicated in antiviral immunity. However, the function of SNX20 in insect antiviral immunity remains poorly defined. In this study, we investigated the role of Bombyx mori SNX20 (BmSNX20) during i...

Jian He, Guang-Yu Ma, Tian-Dong Li et al. · 0 citations
Open access Aug 2026

Tudor staphylococcal nuclease promotes Bombyx mori cytoplasmic polyhedrosis virus replication through lipid metabolic reprogramming in silkworms.

Bombyx mori cytoplasmic polyhedrosis virus (BmCPV), a double-stranded RNA reovirus, causes significant losses in sericulture; however, the host factors that support its replication remain poorly understood. Here, we identify Tudor staphylococcal nuclease (TSN) as a critical pro-viral host factor in silkworms. TSN is a...

M. Awais, Nasir Mehmood, Wen-Sheng Yu et al. · 0 citations
Jul 2026

Bmlebocin3 could inhibit Bombyx mori cytoplasmic polyhedrosis virus in silkworms via the immune deficiency pathway and through the 20-hydroxyecdysone modulations.

Results identify BmLEB3 as a virus-responsive AMP and suggest that its expression is modulated by IMD-associated signalling and hormonal cues during BmCPV infection in B. mori.

M. Awais, Nasir Mehmood, Wen-Sheng Yu et al. · 0 citations

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