Oct 2026
SIRT1 alleviates hypoxia-induced mitochondrial dysfunction and scleral remodeling in scleral fibroblasts by regulating AMPK via FOXO1.
BACKGROUND AND PURPOSE Myopia is a globally prevalent refractive error. Sirtuin 1 (SIRT1) may be involved in myopia progression, but the specific underlying mechanisms remain to be elucidated. This study aimed to investigate the role of SIRT1 in myopia and elucidate its underlying mechanisms. METHODS A mouse myopia m...
Zhi-Juan Hua, Qin Zhu, Xue-Jiao Li et al.
· Cellular Signalling · 0 citations