Jing-Feng Zhao

Folate-decorated nanoparticles deliver bulleyaconitine A to inflammatory macrophages for rheumatoid arthritis therapy.

Rheumatoid arthritis (RA) is a systemic autoimmune disease driven by synovial inflammatory cell infiltration and progressive joint erosion. Macrophages undergo a pathological shift toward an M1 pro-inflammatory phenotype, which plays a critical role in the progression of the disease. Modulation of M1 macrophages may be...