Review
Oct 2026
From functional complexity to structural modification: A systematic review of the ongoing development of targeted PXR drugs.
The structure-activity relationships (SAR), design strategies, and molecular mechanisms of small-molecule PXR modulators from a medicinal chemistry perspective are examined and actionable strategies that integrate emerging technologies and innovative approaches to improve target selectivity and achieve more precise tra...
Meng-Yao Wang, Wu-Yi Wu, Guo-Nian Zhu et al.
· European journal of medicina... · 0 citations