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Jing-Han Xu

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Open access Aug 2026

ACE2-PNA conjugates exploit viral endocytosis for targeted intracellular delivery and exhibit dual antiviral efficacy against SARS-CoV-2

A Receptor-Drug Conjugate (RDC) strategy, in which a therapeutic payload is covalently linked to a decoy receptor, enabling virus-triggered targeted intracellular delivery, and has significant implications for reducing off-target toxicity and enhancing antiviral potency.

Yi-Fei Wang, Jing-Han Xu, Yi-Quan Chen et al. · Molecular Biomedicine · 0 citations