Author

Jing Huang

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Open access Sep 2026

Gut microbial H2S promotes metabolic dysfunction in mice via hepatic PPARα suppression.

This study investigates the role of gut microbiota-derived hydrogen sulfide (H2S) in obesity and glucose metabolism disorders. By integrating human gut metagenomic data, intervention experiments in mouse models, and in vitro cellular assays, we identified a signature of microbial sulfur metabolism in human cohorts and...

Shi-Bo Lei, Xuan Qiu, Zhen Wang et al. · The ISME Journal · 1 citation

Jul 2026

Characterization of a Novel GH3 β-Glucosidase with Alkali-Tolerant and Halophilic Properties from Pontixanthobacter luteolus SW-109.

Local enrichment of acidic residues on the PlGH3 surface could generate a negative electrostatic potential, which enables adaptation to high-salt and alkaline environments, thereby sustaining the enzyme's catalytic activity under such extreme conditions.

Kaijuan Wu, Ke Guo, Zheng Yu et al. · Applied Biochemistry and Bio... · 0 citations