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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Jing-Hui Jin

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Sep 2026

Celastrol induces mitochondrial apoptosis in hepatocellular carcinoma by suppressing LRP6-associated Wnt/β-catenin signaling.

Celastrol, a quinone methide triterpenoid derived from the root bark of Tripterygium wilfordii Hook. f., has antitumor activity, but its molecular mechanisms in hepatocellular carcinoma (HCC) remain incompletely defined. This study investigated whether celastrol suppresses HCC through LRP6-associated modulation of Wnt/...

Yi-Xuan Wang, Dan-Dan Wang, Jing-Hao Fu et al. · 0 citations

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