Jing-Jing Liu

46 TKI Resistance is Associated with Immune Dysfunction in ccRCC

It is observed that sunitinib treatment leads to a marked reduction in endothelial cells and cancer‑associated fibroblasts, confirming a massive collapse of the vascular and perivascular niche, and identified two major tumor cell populations that adapt in distinct ways to sunitinib exposure and the resulting vascular c...