Author

Jing-Jing Pu

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Review Open access Aug 2026

Protein palmitoylation in hematological malignancies: mechanistic links to lipid metabolic reprogramming and therapy resistance

Protein palmitoylation has emerged as a central post-translational mechanism governing protein localization, stability, and signal transduction. In hematological malignancies, this dynamic modification lies at the intersection of lipid metabolic reprogramming, tumor–immune interactions, and therapeutic resistance. Here...

Qian Zhao, Jian-Gang Mei, Si-Qi Qian et al. · Frontiers in Immunology · 0 citations

Jul 2026

Rational design and synthesis of TBC1D2 inhibitors: Augmenting autophagy to improve sorafenib sensitivity in hepatocellular carcinoma.

G2 is established as a promising therapeutic candidate for surmounting sorafenib resistance, characterized by selective antitumor activity against malignant hepatocellular carcinoma.

Keyan Han, Yuqi Lin, Yu Huang et al. · European journal of medicina... · 0 citations

Review Open access Jul 2026

Advances in improving cancer immunotherapy with nanotechnology: from smart nanoparticles to synergistic combination strategies

This review comprehensively highlights the latest advancements in using nanotechnology to enhance cancer immunotherapy and highlights synergistic effects achieved by combining nanoparticles with other treatments like chemotherapy, radiation, photothermal/photodynamic therapy, and more, which can turn hard-to-treat tumo...

U. Cho, Jing-Jing Pu, Amit Sharma et al. · Molecular Cancer · 0 citations