Sep 2026
Repurposing GS-441524 to inhibit biofilm formation and virulence of Bacillus cereus
Abstract Bacillus cereus is a resilient foodborne pathogen, with biofilm formation and virulence regulated by quorum sensing (QS). This study evaluates GS-441524, the active metabolite of remdesivir, as an anti-virulence agent against B. cereus. At sub-inhibitory concentrations, GS-441524 dose-dependently reduced prote...
Kai-Zhong Xu, Di Meng, Lu-Jun Yin et al.
· Biofouling (Print) · 0 citations