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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Jing Li

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Open access Aug 2026

AMOTL2 inhibits lymph node metastasis in gastric cancer by suppressing TGF-β/Smad signaling and is destabilized by the E3 ubiquitin ligase SMURF1

Findings define AMOTL2 as a potential suppressor of GC progression that is destabilized by SMURF1, suggesting that the SMURF1-AMOTL2-Smad signaling axis may contribute to GC progression and lymphatic dissemination, representing a candidate therapeutic target that warrants further validation.

Hui-Zhen Wang, Bo Yang, Chang-Qing Lin et al. · 0 citations

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