Open access
Sep 2026
Sodium alginate-based dual-responsive nanoparticles co-loaded with baicalin and doxorubicin induce ferroptosis in hepatocellular carcinoma associated with the PI3K/AKT/FoxO3α axis regulation
The marine polysaccharide carrier overcomes BAI and DOX solubility/toxicity defects, creates a practical HCC combinatorial nanotherapy, and defines a potential correlation between the PI3K/AKT/FOXO3α regulatory axis and hepatic cancer ferroptosis.
Xi-Ning Li, Ming-Jie Bian, Jing Li
· Frontiers in Cell and Develo... · 0 citations