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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Jing Lin

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Open access Aug 2026

SPATS2 triggers immune evasion and anti-PD-1 resistance of hepatocellular carcinoma by inducing dendritic cell phagocytic dysfunction

The clinical efficacy of anti-PD-1 immunotherapy in hepatocellular carcinoma (HCC) remains limited due to the inherently immunosuppressive tumor microenvironment. This study aims to investigate the role of the spermatogenesis-associated serine-rich protein 2 (SPATS2) in mediating resistance to anti-PD-1 immunothe...

Bo Zhang, Xiang-Yu Wang, Bao-Rui Tao et al. · 0 citations

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