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Jing-Ting Xu

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Review Open access Sep 2026

The role of mTORC2/RICTOR in immune cells and inflammatory diseases

mTORC2, defined by its core component RICTOR, is a key regulator of immune cell function and inflammation, yet its roles have long been underappreciated due to lack of specific inhibitors and in vivo tools. This review summarizes the current understanding of mTORC2-specific signaling (via AKT, SGK1, and PKC) in regulat...

Jing-Ting Xu, Wen-Xing Zhong, Fei Xin et al. · 0 citations

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