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Open access Aug 2026

Benchmarking Antibody Modeling Tools across Structure Prediction, Docking, and Paratope–Epitope Interface Analysis

This work evaluated ImmuneBuilder, IgFold, AlphaFold3, GRAMM, and dyMEAN on 50 non-redundant humanized antibody–antigen complexes using multiple retained predictions and paired statistical testing, finding all three antibody structure predictors were accurate.

Zeyuan Yu, Jilei Wu, Ziyao Ning et al. · 0 citations