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Jing-Wen Luo

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Open access Aug 2026

A multi-omics integrative analyses reveals CYBB-mediated apoptotic and immune dysregulation as a key target of berberine in diffuse large B-cell lymphoma

This integrative study identifies berberine-related genes with potential causal relevance to DLBCL and prioritizes CYBB as a functionally relevant target linked to apoptosis, immune regulation, and prognosis, highlighting the potential involvement of berberine–CYBB axis underlying berberine activity in DLBCL.

Jie-Wen Tan, Yun-Man Xu, Yue-Ping He et al. · Frontiers in Pharmacology · 0 citations