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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Jingwen Zhang

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3 papers indexed here

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Review Open access Oct 2026

Natural polysaccharides as modulators of mitochondrial homeostasis: structural determinants, pharmacological mechanisms, and translational challenges

Mitochondrial dysfunction is a convergent pathological feature of neurodegenerative, metabolic, cardiovascular, hepatic, and cancer-related disorders, making mitochondrial homeostasis an important therapeutic target. Natural polysaccharides (NPs) are structurally diverse macromolecules that have emerged as promising mu...

Xin-Fang Du, Jing-Wen Zhang, Wen-Jing Li et al. · 0 citations
Open access Sep 2026

Sestrin2 mitigates obesity-associated HFpEF via adaptive IRE1α-XBP1 signaling and redox regulation.

It is demonstrated that Sestrin2 has cardioprotective effects on obesity-associated HFpEF and is associated with the activation of adaptive IRE1α-XBP1 signaling involving Sigmar1, together with improved metabolic and redox homeostasis.

Ke-Xin Zhang, Cheng-Xia Kan, Jing-Wen Zhang et al. · 0 citations
Review Jul 2026

Mitophagy in Cardiovascular Disease: From Mechanistic Insights to Therapeutic Horizons.

The roles of mitophagy in various cardiovascular pathologies, including cardiac aging, myocardial hypertrophy, heart failure, myocardial infarction, ischemia-reperfusion injury, are summarized.

Deyi Guo, Kun Wang, Jing-Wen Zhang et al. · 1 citation

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